PAX6 anticorps (C-Term)
Aperçu rapide pour PAX6 anticorps (C-Term) (ABIN5517237)
Antigène
Voir toutes PAX6 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Séquence
- PSVNGRSYDT YTPPHMQTHM NSQPMGTSGT TSTGLISPGV SVPVQVPGSE
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against PAX6. It was validated on Western Blot.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human PAX6
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PAX6 (Paired Box 6 (PAX6))
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Autre désignation
- PAX6
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Sujet
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This gene encodes paired box gene 6, one of many human homologs of the Drosophila melanogaster gene prd. In addition to the hallmark feature of this gene family, a conserved paired box domain, the encoded protein also contains a homeo box domain. Both domains are known to bind DNA and function as regulators of gene transcription. This gene is expressed in the developing nervous system, and in developing eyes. Mutations in this gene are known to cause ocular disorders such as aniridia and Peter's anomaly. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: Name=PAX6,
Protein Interaction Partner: IPO13, Dlg4, NKIRAS2, Cacnb3, Pax6, Diap1, SMAD5, SMAD4, SMAD3, SMAD1, AR, HIPK2, SUMO1, SMARCA4, TP73, SHANK3, PBX1, VSX2, EN1, TRIM11, HOMER3, SIX3, INADL, EP300, SOX10, RGS3, DIAPH1, MAFG, RAX, DYNLL1, DLG1, CDX2, TBP, SOX3, MITF, HOXB1, SOX2, LHX2, TA
Protein Size: 422 -
ID gène
- 5080
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NCBI Accession
- XP_005253013
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UniProt
- P26367
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Pathways
- Peptide Hormone Metabolism, Carbohydrate Homeostasis
Antigène
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